Xi Lin,1 Cai Chang,2,3 Changjun Wu,4 Qin Chen,5 Yulan Peng,6 Baoming Luo,7 Lina Tang,8 Jing Li,9 Jihui Zheng,10 Ruhai Zhou,11 Guanghe Cui,12 Ao Li,13 Xuemei Wang,14 Linxue Qian,15 Jianxing Zhang,16 Chaoyang Wen,17 Joel Gay,18 Huili Zhang,18 Anhua Li,1 Yaling Chen2,3 1State Key Laboratory of Oncology in Southern China, Department of Ultrasound, Sun
Population genetics and molecular xenomonitoring of Biomphalaria freshwater snails along the southern shoreline of Lake Malawi, Malawi
Abstract Background Intestinal schistosomiasis was confirmed endemic in Mangochi District, Malawi, in May of 2018 following an unexpected encounter with discreet populations of Biomphalaria spp.freshwater snails during routine malacological surveillance activities.Since then, only limited malacological surveillance of Biomphalaria has been carried
Substantial generalization of sensorimotor learning from bilateral to unilateral movement conditions.
Controversy exists regarding whether bimanual skill learning can generalize to unimanual performance.For example, some investigators showed that dynamic adaptation could only partially generalize between bilateral and unilateral movement conditions, while others demonstrated complete generalization of visuomotor adaptation.Here, we identified three
Junctional ER Organization Affects Mechanotransduction at Cadherin-Mediated Adhesions
Cadherin-mediated adhesions (also known as adherens junctions) are adhesive complexes that connect neighboring cells in a tissue.While the role of the actin cytoskeleton in withstanding tension at these sites of contact is well documented, little is known about the involvement of microtubules and the associated endoplasmic reticulum (ER) Jolie Tank
Electrophiles against (Skin) Diseases: More Than Nrf2
The skin represents an indispensable barrier between the organism and the environment and is the first line of defense against exogenous insults.The transcription factor NRF2 is a central regulator of cytoprotection and stress resistance.NRF2 is activated in response to oxidative stress by reactive oxygen species (ROS) and electrophiles.These elect